The Evidence Digest Advertorial Issue 47 · 22.09.2026
Close-up of fresh dark blueberries filling the frame

Nutrition · Five papers, one thread

What the Research Really Says About Deeply Coloured Foods and Staying Sharp

Compiled by Tomás Reyes · 6 min read

In brief

§01 — Where the habit came from

A spoonful a day, repeated a million times

The advice has been circulating for years: raw honey, one spoon, first thing in the morning, to help keep the mind clear. It spreads easily because it is cheap, pleasant and sounds plausible.

And the plausibility is earned. Honey carries antioxidant and anti-inflammatory plant compounds, and a 2023 review in Oxidative Medicine and Cellular Longevity catalogued the ones showing the most promise for supporting the brain.1

What the advice never specifies is which compounds, or how much of them a spoon actually contains. That is the gap this digest is about.

§02 — The papers

Three independent lines pointing the same way

Across quite different study designs, the same pigment family keeps surfacing: anthocyanins, responsible for the deep colour of blueberries, blackcurrants, purple grapes and certain dark honeys.

PaperWhat it examinedWhat it reportedRef.
Systematic review, Mol Nutr Food Res (2021) Berry anthocyanins, cognitive performance and vascular function Consistent signals across trials, judged worth further study [2]
Controlled study, J Agric Food Chem (2010) Older adults drinking wild blueberry juice daily for 12 weeks Better scores on learning and word-recall tasks [3]
Meta-analysis of randomised trials Pooled anthocyanin supplementation results Favourable effects on short-term memory, verbal learning, executive function [4]

What this supports

  • Anthocyanins are the component researchers keep measuring
  • Concentration matters more than the ritual itself
  • Dietary intake and supplementation have both been trialled

What it doesn't settle

  • How much of the effect any one person should expect
  • Trial sizes vary, and some are small
  • Whether honey specifically was the source in these studies

Read plainly, the literature narrows the question rather than answering it outright: if the pigments are the part that matters, then the pigment density of the food is what deserves attention.

An overhead spread of fresh vegetables, eggs and greens on a wooden table
// Colour density across the plate is the practical version of the same idea.

§03 — Source material

Why two jars of honey are not the same product

Honey inherits its character from the flowers, soil and altitude behind it. Blended supermarket honey tends to be pale and light on pigment. Wild honey from mineral-rich terrain runs darker and denser.

That is what took this particular team to the hills of Ikaria, a small island in the eastern Aegean, where the honey comes out notably dark.

Ikaria is already familiar territory in longevity research: it is one of the handful of regions classed as Blue Zones, where living past ninety while staying active, social and quick in conversation is ordinary. The honey does not explain the island — but it is a sensible place to go looking for a denser source.

§04 — Mechanism

The brain runs on delivered fuel

The brain accounts for around two percent of body weight and roughly twenty percent of daily energy use, almost all of it glucose. That fuel arrives through healthy circulation and has to be used efficiently once it does.

Anthocyanins are studied on both sides of that: antioxidant activity at the cellular level, and support for the healthy blood flow that handles delivery.2 Sleep, movement and a varied diet do the rest of the work.

§05 — The formula

MemoFlow, in specification form

MemoFlow® — two actives, one island
Active 01
Concentrated anthocyaninsFrom wild honey gathered in Ikaria's mountains. Antioxidant support plus healthy circulation.
Active 02
Natural lithium orotateA trace mineral from the island's springs, at the level found in mineral water and everyday foods.5
Format
Sublingual drops — two under the tongue each morning, roughly ten seconds.
Not included
No stimulants, no hormones, no capsules, no powders.
Guarantee
90 days, full refund, no explanation required.

Lithium in this form is a naturally-occurring trace mineral rather than a medication — it turns up daily in drinking water, grains and vegetables, and nutrition researchers have studied its dietary role for decades.5

Primary source

Full ingredient breakdown, sourcing and current pricing

Open the MemoFlow page → 90-day money-back guarantee · Free shipping

§06 — Field notes

What people using it report back

“Names and words arrive when I want them. I notice it most in conversation.”

Yvonne, 68

“Clear mornings, no fuss. Ten seconds and I'm on with the day.”

Douglas, 74

“I'm on form at dinner — the long stories, all the details in order.”

Colette, 70

These are individual accounts rather than trial data. Their value here is that the themes — clarity, ease, focus — line up with what the papers above explore.

§07 — Queries

Reader questions

Is ordinary honey still worth eating?

Yes. It remains a pleasant natural food. It simply tends to be low in anthocyanins, and the research above works with considerably higher amounts.

What kind of lithium is in the formula?

Natural lithium orotate, in a trace amount comparable to mineral-rich spring water and common foods.5 It sits at nutrient level.

Why drops instead of a capsule?

Sublingual delivery uses the tissue under the tongue, which is why the routine is two drops rather than something to swallow with water.

Next step

Read the formula details for yourself

Learn more about MemoFlow → 90-day money-back guarantee · Free shipping

References

  1. Al-Shahi R, et al. Honey on brain health: a promising brain booster. Oxid Med Cell Longev, 2023. PMID 36733498
  2. Ahles S, et al. Effects of berry anthocyanins on cognitive performance, vascular function and cardiometabolic risk markers: a systematic review. Mol Nutr Food Res, 2021. PMC8234025
  3. Krikorian R, et al. Blueberry supplementation improves memory in older adults. J Agric Food Chem, 2010;58(7):3996–4000. PMID 20047325
  4. The effect of anthocyanins on cognition: a systematic review and meta-analysis of randomized clinical trial studies. PMC11775034
  5. Schrauzer GN. Lithium: occurrence, dietary intakes, nutritional essentiality. J Am Coll Nutr, 2002;21(1):14–21. PMID 11838882